Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...

The partners are launching ImmuneScape, a multiomics program using spatial and single-cell sequencing to study immune drivers ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance. Emerging evidence indicates that ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...