Thiazide diuretics remain as one of the drugs most commonly used to treat systemic arterial hypertension. In particular, hydrochlorothiazide (HCTZ) is one of the first-line antihypertensive therapy ...

The muscular system works to control the movement of our body and internal organs. Muscle tissue contains something called muscle fibers. Muscle fibers consist of a single muscle cell. They help to ...

In a preclinical study, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle ...

How muscle changes with ageing, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of ageing muscles in humans. Researchers ...

A research team reports that muscle-invasive bladder cancer (MIBC) is dangerous not only because tumor cells breach the bladder’s detrusor muscle, but also because that invasion can reprogram the ...

Muscles make up nearly 40% of the human body and power every move we make, from a child’s first steps to recovery after injury. For some, however, muscle development goes awry, leading to weakness, ...

Duke University researchers say they have created an artificial human heart muscle large enough to patch over damage seen in patients who have suffered a heart attack. The advance takes a major step ...

Muscle-on-chip systems are three-dimensional human muscle cell bundles cultured on collagen scaffolds. A Stanford University research team sent some of these systems to the International Space Station ...

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches ...

Skeletal muscle is the type of muscle that controls movement. Problems with these muscles can be minor, life-threatening, or ongoing problems that make it hard to perform basic daily activities.