Calcium signalling is a pivotal regulatory mechanism in ciliated protozoa, orchestrating a myriad of cellular processes from ciliary beating to membrane trafficking. Recent studies have illuminated ...

The cell's endoplasmic reticulum (ER) plays a central role in protein synthesis, folding, and calcium (Ca²⁺) storage. When ...

Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations. Existing GECIs are often sensitive to pH ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Cerebral blood delivery depends on mechanisms such as electrical signaling, which propagates through capillary networks to upstream arterioles to deliver blood, and calcium signaling, which fine-tunes ...

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to ...

A study published in Nature Communications examined the use of calcium carbonate nanoparticles (CNPs) to improve the activation and function of cytotoxic T lymphocytes (CTLs) in cancer immunotherapy.

Researchers are closer to understanding what drives the autoimmune disorder Sj gren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

A new method exposes key details of the mechanism behind calcium signaling in prokaryotes for the first time. Working in a Listeria monocytogenes model, researchers from Umeå University (Sweden) led ...