The clinical significance of a copy number variant is usually determined either by observing whether the associated phenotype segregates along with the variant within a family, the rearrangement being ...

It is an open question whether in multiple myeloma (MM) bone marrow stromal cells contain genomic alterations, which may contribute to the pathogenesis of the disease. We conducted an array-based ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Array CGH describes a technology in which microarrays comprised of well-defined DNA probes are used to screen DNA test samples to detect changes in sequence copy number. For whole-genome aCGH, genomic ...

MADISON, Wis.--(BUSINESS WIRE)--Roche NimbleGen, Inc. has launched NimbleGen Comparative Genomic Hybridization (CGH) microarrays in a 12x135K format for analysis of DNA copy number variation.