Basal cell carcinoma has low immunogenicity. Tumor cells express Foxc1 protein (red), which suppresses HLA class I (green) in the tumor cells. Compromised antigen presentation ranks among the top ...

Antigens are a critical part of the immune system; they are present on many types of cells, and can be made of proteins, lipids, sugars, and ... | Cell And Molecular Biology ...

A new discovery about how cells communicate with each other in the body’s immune system has revealed deeper insights for an international team of scientists into fundamental immune system function.

Liquid biopsy-based prediction of clinical benefit from immune checkpoint inhibitors in advanced biliary tract cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

1. Antigen preparation: Scientists can produce cancer vaccines against tumors by using the patient’s tumor as a source of antigen or by synthesizing peptides from tumor antigens. 2. Antigen delivery: ...

How does the gut cause Multiple Sclerosis? New research identifies the MHC II protein in intestinal epithelial cells as the trigger for MS-related neuroinflammation. Discover how gut-primed T cells ...

Invariant natural killer T cells have emerged as a potentially versatile allogeneic platform for blood cancer immunotherapy, ...